Objectives We developed carbonated beverage containing resistant maltodextrin（RMD）. A randomized, double-blind crossover study was carried out to investigate whether the beverage would suppress the postprandial elevation of the serum triglyceride（TG）levels, remnant like lipoprotein particle（RLP）-cholesterol levels. Also, two randomized double-blind placebo-controlled studies were carried out to assess the safety of excessive or long-term intake of the beverage.
Methods The subjects were 90 healthy volunteers（serum TG：120-200 mg/dL）. The subjects ingested a test beverage containing RMD（5 g）or beverage without RMD（placebo）together with fat-rich meal（lipid：42.1 g）. Blood samples were drawn before and 2, 3, 4 and 6 hours after ingestion, and the serum triglyceride levels were measured. The subject for safety evaluation of long-term intake was 30 healthy volunteers, including 10 volunteers whose serum TG levels were 150-200 mg/dL. They consumed one bottle of test beverage（485 mL/bottle）containing RMD（5 g）at a meal per day for 12 weeks. The subject for safety evaluation of excessive intake was 30 healthy volunteers, including 10 volunteers whose serum TG levels were 150-200 mg/dL. They consumed one bottle of test beverage containing RMD（15 g）at a meal per day for 4 weeks.
Results Intake of RMD beverage significantly suppressed the level of serum TG observed at 2, 3 and 4 hours after food ingestion as compared with that of the placebo（P＜0.05）. Postprandial RLP-cholesterol elevation also significantly suppressed at 3, 4 and 6 hours after food ingestion as compared with that of the placebo（P＜0.05）. Also, there were no clinical problems in the blood examinations and physical examinations. No adverse reactions were observed.
Conclusions These results indicated that intake of the RMD supplemented beverage suppresses postprandial serum triglyceride levels without any safety problem.