Effects of Intake of Lactobacillus casei subsp. casei 327 on Skin Conditions of Young Women
−A Randomized Double-blind, Placebo-controlled, Parallel-group Study−

Objective The aim of this study was to evaluate the effects of intake of heat-killed Lactobacillus casei subsp. casei 327(327 strain)on young women's skin conditions.
Methods A randomized, double-blind, placebo-controlled, parallel-group study was conducted for 60 young women. The volunteers were administered test food containing 50 mg(approximately 1×1011 bacteria)of heat-killed 327 strain or placebo food for 6 weeks. The levels of stratum corneum hydration and transepidermal water loss(TEWL)and score of skin surface texture were measured at the right cheek.
Results Data of 54 subjects(n=27 each)were obtained and analyzed. No clear statistically significant differences were observed in both groups. But TEWL of 327 strain intake group showed a lower tendency than that of placebo food group. In analysis subcategory with high level of TEWL, the TEWL of 327 strain intake group(n=10)was significantly lower than that of placebo food group(n=14)at 4 weeks.
Conclusions Intake of 327 strain seems to have a skin dryness inhibiting effect.