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Vol. 53　No. 11　2025

Ethical considerations for the inclusion of patient-reported outcomes in clinical research : The PRO ethics guidelines

T. Miyaji, et al.

Jpn Pharmacol Ther　2025　53（11）935-50

Effects of continuous intake of nutritional supplement containing chondroitin sulfate oligosaccharides for 12 weeks on blood pressure reduction and blood vessels in healthy adults with high blood pressure
―A randomized, double‒blind, placebo‒controlled, parallel‒group study―

N. Miyamoto, et al.

Jpn Pharmacol Ther　2025　53（11）959-72

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Consumption of foods containing eggshell‒derived hydroxyapatite improves the oral environment
―A randomized, double‒blind, placebo‒controlled, parallel‒group study―

Y. Higuchi, et al.

Jpn Pharmacol Ther　2025　53（11）973-86

QALY shortfall and severity weighting in cost‒effectiveness evaluations
―Insights and lessons from the UK, Norway, and the Netherlands for Japan―

M. Enami, et al.

Jpn Pharmacol Ther　2025　53（11）989-1001